What drug is given for benzodiazapine overdose or sedation reversal? flumazanil What is the MOA of flumazanil antagonizes benzodiazapine receptors (pharmacologic antagonist) What is the black box warning associated w/ flumazanil? seizure risk When is flumazanil contraindicated? tricyclic antidepressant overdoseĬurrent seizure or high seizure risk What are the adverse effects assoc/ with flumazenil? seizure, nausea, vomiting, agitation, heart rate changes What is Digibind given for? Digoxin overdose with ventricular arrhythmia, some bradycardias. What are the adverse effects of N-acetylscysteine? bronchospasm, cough, nausea, vomiting What should be monitored in a patient who is given N-acetylcysteine? AST, ALT, acetaminophen levels. Also is an antioxidant and NMDA receptor modulator. also breaks disulfide bonds thinning the mucus.
Replenishes glutathione which is required to metabolize acetaminophen to NAPQI. What is the adverse effect of activated charcoal? dark stools What chemicals/toxins can activated charcoal not be used for? iron, lithium, potassium, alkali, corrosive mineral acids, alcohols, cyanide What drug is given for tylonol toxicity? What is its MOA? N-acetylcysteine.
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